Example httpd.conf section for a Paste app with an ini file:

<Location />
    SetHandler python-program
    PythonHandler paste.modpython
    PythonOption paste.ini /some/location/your/pasteconfig.ini
</Location>

Or if you want to load a WSGI application under /your/homedir in the module startup and the WSGI app is app:

<Location />
    SetHandler python-program
    PythonHandler paste.modpython
    PythonPath "['/virtual/project/directory'] + sys.path"
    PythonOption wsgi.application startup::app
</Location>

If you'd like to use a virtual installation, make sure to add it in the path like so:

<Location />
    SetHandler python-program
    PythonHandler paste.modpython
    PythonPath "['/virtual/project/directory', '/virtual/lib/python2.4/'] + sys.path"
    PythonOption paste.ini /virtual/project/directory/pasteconfig.ini
</Location>

Some WSGI implementations assume that the SCRIPT_NAME environ variable will always be equal to "the root URL of the app"; Apache probably won't act as you expect in that case. You can add another PythonOption directive to tell modpython_gateway to force that behavior:

PythonOption SCRIPT_NAME /mcontrol

Some WSGI applications need to be cleaned up when Apache exits. You can register a cleanup handler with yet another PythonOption directive:

PythonOption wsgi.cleanup module::function

The module.function will be called with no arguments on server shutdown, once for each child process or thread.

This module highly based on Robert Brewer's, here: http://projects.amor.org/misc/svn/modpython_gateway.py